From owner-btk-mca@hgmp.mrc.ac.uk Thu Nov 27 09:14:20 2003 Return-Path: X-Original-To: btk-mca-outgoing Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with SMTP id 714877D4AA for ; Thu, 27 Nov 2003 09:14:20 +0000 (GMT) X-Original-To: btk-mca-list@hgmp.mrc.ac.uk Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id EDF647D638 for ; Thu, 27 Nov 2003 09:14:19 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6068) id 2BF6E7D4AA; Thu, 27 Nov 2003 09:14:19 +0000 (GMT) X-Original-To: bionet-metabolic-reg@net.bio.net Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 862197D60F for ; Wed, 26 Nov 2003 20:18:58 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 60001) id C72E57D589; Wed, 26 Nov 2003 20:18:45 +0000 (GMT) To: bionet-metabolic-reg@net.bio.net From: bs0dk@bath.ac.uk (dan kerley) Newsgroups: bionet.metabolic-reg Subject: Teaching MCA Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: <34894776.1069877848@[172.20.6.46]> MIME-Version: 1.0 Content-Type: text/plain; charset=us-ascii; format=flowed Content-Transfer-Encoding: 7bit Content-Disposition: inline X-Original-To: btk-mca@net.bio.net X-Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 203387D220 for ; Wed, 26 Nov 2003 20:18:44 +0000 (GMT) X-Received: from roche.bath.ac.uk (roche.bath.ac.uk [138.38.32.21]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id C44E37D60F for ; Wed, 26 Nov 2003 20:18:34 +0000 (GMT) X-Received: from mary.bath.ac.uk ([138.38.32.14] ident=mmdf) by roche.bath.ac.uk with smtp id 1AP67K-00014X-9S for btk-mca@net.bio.net; Wed, 26 Nov 2003 20:18:30 +0000 X-Received: from [172.20.6.46] ( papc-lc4-46.campus.bath.ac.uk [172.20.6.46] ) by bath.ac.uk id aa15669 for ; 26 Nov 2003 20:17 +0000 X-To: btk-mca@net.bio.net X-Originator-Info: login-id=bs0dk; server=imaphost.bath.ac.uk X-Mailer: Mulberry/3.0.3 (Win32) X-Scanner: c236fa3822cc3559531dd6114774a1f3b5503b5d Date: Thu, 27 Nov 2003 09:14:19 +0000 (GMT) Sender: owner-btk-mca@hgmp.mrc.ac.uk Precedence: bulk Hi, I'm not sure how successful this will be as there don't seem to have been many posts for a while! I would appreciate any suggestions about the best way to explain the basics of MCA. I am a Biochemistry final year undergraduate at the University of Bath and will be presenting a seminar (approx 1 hour) to my fellow students on MCA and its applications. We have a grounding in enzyme kinetics, but no previous knowledge of MCA (well, I personally understand the basics now!). If possible I would like to minimise the mathematical aspect of MCA whilst still explaining what all the formulae mean and how they are applied-no matrices please! Instead I will focus on why it is relevant. Has anyone tried to teach MCA before? what are the applications-drug design, fermentation etc? any examples of where it has actually been used in industry? Thanks very much for your help. Best regards, Dan Kerley, University of Bath. PS: I gather the consensus opinion is the format dlny/dlnx is preferable to (x/y)(dy/dx) ?? --- .