-----===[[[ A I D S w i r e D I G E S T 05.31.93 ]]]===----- Insurers Accused of Discrimination in AIDS Cover * New York Times (06/01/93) Freudenheim, Milt As a result of the loss of vital medical benefits, more and more AIDS patients are accusing their health insurers of discrimination prohibited under the Americans With Disabilities Act of 1990. The U.S. Equal Employment Opportunity Commission has received several dozen complaints involving health insurance plans that have canceled or limited coverage for AIDS patients. According to the law's insurance provisions, which were enacted last July, insurers may restrict their policies to avoid risk, but not as a means to escape discrimination claims. The cases have emerged after many health insurance plans have taken advantage of federal court rulings that have allowed some groups to deny or limit coverage for expensive diseases. One case appealed to the Supreme Court last fall would not be heard because of recommendations from the Bush administration. The case involves H & H Music Company of Houston, Texas, which drastically reduced medical benefits after its employee John W. McGann became severely ill. The company, which was self- insured, said it could not afford to cover AIDS. The lower tribunals decided that self-insured employers, such as H & H Music, were exempt from state regulation under the 1974 Employee Retirement Income Security Act. President Clinton previously chastised the Bush administration for siding with the employer in the case, saying the case demonstrated the need for national health care. But Clinton has not yet appointed a chairman to the EEOC, which has kept the commission virtually paralyzed in the case for months. Body May Fight AIDS With Wrong Weapons * Toronto Globe and Mail (Canada) (05/28/93), P. A4 Hess, Henry The human immune system fails to defeat some invaders, such as HIV infection, because it selects the wrong weapons, according to an article published in Friday's issue of Science. The study, by a team of researchers that includes Jonas Salk, the discoverer of the polio vaccine, indicates that the body's defenses fight themselves by attempting to combat HIV with antibodies instead of T-lymphocytes that attack and kill the infected cells. The study proposes a strategy by which AIDS vaccine researchers can produce and "lock in" an effective and long-lasting immunity. It also suggests that much of the current AIDS research is on the wrong track. Peter Bretscher, a microbiologist at the University of Saskatchewan and co-author of the article, said in most humans, the immune system tries to fight HIV by producing antibodies. However, against slow- growing viruses like HIV, the cell-mediated response, which produces killer cells that recognize and destroy HIV-positive cells, is inhibited. Vaccines typically work by priming the body to recognize and respond quickly to infection by a specific disease-causing agent, said Dr. Bretscher. The study indicates that exposure to very low doses of HIV will incite the desired cell-mediated immune response, while higher exposures produce an antibody-mediated response that suppresses the cellular response. Dr. Bretscher said that mobilizing the less discriminating T-lymphocytes produces "a much more vicious kind of immunity" with a higher risk of damage to uninfected body cells, but one more likely to be effective against HIV. Housing Crisis Intensifies for People With AIDS * Baltimore Sun (06/01/93), P. 1B Selby, Holly AIDS activists and community leaders in the Baltimore, Md., area have formed a panel to devise a 10-year strategy for dealing with what they consider a rapidly growing housing crisis for AIDS patients. City officials began accepting proposals two weeks ago from nonprofit organizations on how to develop such a strategy to deal with the increasing numbers of AIDS patients who are too ill to work and too poor to afford a home. The 10-year plan will address the needs of AIDS patients in the city of Baltimore, Baltimore County, and Anne Arundel County--a jurisdiction created by the federal government for funding purposes, says Donna Poggi Keck, special projects coordinator in the city department of housing. Money that will fund the plan comes from $447,000 provided for the Baltimore jurisdiction last year by the U.S. Department of Housing and Urban Development under the Housing Opportunities for Persons with AIDS Act (HOPWA). Another $1.1 million will be available next year for AIDS-related services in the area. Approximately $57,000 was designated to create the 10-year plan, while most of the remaining money goes to a rental assistance program for AIDS patients. Keck says that 80 to 100 area residents receive subsidies. She adds that Baltimore and the two counties are the only jurisdictions in Maryland to receive the HUD funding, which was based on the prevalence of AIDS cases in the area. Due to the high AIDS case rate in Baltimore, the city receives about 80 percent of the grant. In the Age of AIDS, Sex Clubs Are Back in N.Y. * Philadelphia Inquirer (05/31/93), P. A1 Maykuth, Andrew Less than a decade after the state of New York passed regulations that threatened to close the remaining sex clubs in New York City, the popularity of such establishments has re- emerged. Because of the threat of AIDS, in 1985, the state classified fellatio and anal intercourse in commercial establishments as "public-health nuisances." But now several dozen sex clubs and bathhouses have made a comeback, causing renewed debate in a city where 200,000 AIDS cases have been reported since the disease was first identified. Most of the sex clubs are little more than designated rooms in bars, theaters, and bookstores, and they cater to both gay and straight customers. Their resurgence has prompted arguments from some politicians who want the clubs closed, and say they are breeding grounds for HIV infection. Although city health officials agree that something must be done about the potential for infection, they believe the very existence of sex clubs shows that their power is limited. Mark Barnes, the city's associate health commissioner for policy, said, "I think the health department sends a very bad message if it knows this kind of unprotected intercourse goes on, when the city and the nation are in the midst of a raging epidemic." Nevertheless, he said that "public health is not about morals or taste or aesthetics. It's really about what transmits disease." City officials and civil libertarians are attempting to develop a strategy to regulate, rather than close, the clubs. Health officials want clubs to hire monitors to prevent patrons from engaging in high-risk behavior, although officials concede that it would be difficult to police sexual activities. Sperm Doctor Releases AIDS Test Results * United Press International (05/28/93) (New York) A New York City doctor who was accused of illegally supplying his own semen for artificial insemination has revealed his HIV test results to 10 doctors who performed the inseminations. Peter Slocum, a spokesman for the state health department, said Dr. Douglas Moss, a gynecologist, had not given the department permission to disclose test results even though both the physician and his lawyer have claimed the results were HIV-negative. Moss and medical technician Jerald Tedeschi are being investigated by special state prosecutor Edward Kuriansky at the request of the health department. They face discipline for operating an illegal sperm bank and may also face criminal charges as a result of Kuriansky's findings. In addition, Tedeschi had given permission for his own HIV tests to be made available to sperm recipients. The health department accused the two of breaching several regulations, including using their own sperm while implying the sperm came from a bank of donors, using fresh semen that had not been frozen and quarantined for HIV tests, and selling sperm for a profit. Packaging Reality: Is the Female Condom Better Than We've Been Told? * Village Voice (05/19/93-05/25/93) Vol. 38, No. 21, P. 25 Coleman, Beth The Food and Drug Administration's recent approval of the Reality Female Condom was received with continued doubt of the condom's efficacy. This reaction was due to the resistance to the device by the FDA itself. The agency continues to ignore that women constitute the fastest-growing AIDS population. The FDA requires that the Reality package must state that the male latex condom remains the best protection against HIV and other sexually transmitted diseases. But Dr. Erica Gollub of the HIV Center for Clinical and Behavioral Studies, affiliated with Columbia University in New York City, argues that "Male condoms have never been subjected to the rigors that female condoms, and all new birth control in fact, have been put under." Mary Ann Leeper, senior VP of development at Wisconsin Pharmacal, Reality's manufacturer, said that in laboratory tests, the female condom could not be permeated by HIV or various other sexually transmitted viruses. "If you use it and it doesn't rip or tear it's going to protect you," she said. The rip and tear rate in clinical trials was 0.2 percent, whereas the rip and tear numbers for the male condom is as high as 14 percent. One of the reasons for the delay of Reality's release is the FDA's finding of a 26 percent rate of pregnancy protection. According to Wisconsin Pharmacal and Gollub, the number is a result of bad math, bad science, and the FDA's bias toward male condoms. Mayors Dole Out $1 Million in AIDS Prevention Grants * Nation's Health (05/93-06/93) Vol. 23, No. 5, P. 4 The U.S. Conference of Mayors allotted $1 million to be used by community-based groups and health departments in 10 cities for establishing AIDS prevention programs for populations at high risk of HIV infection. The grants are intended to spur a collaborative anti-AIDS effort among community groups and local health departments. The groups which received 1993 Collaborative HIV Prevention Grants included: the Boston AIDS Consortium, $120,095 to satisfy the unmet needs of HIV/AIDS prevention and education; the Kansas City, Mo., Health Department, $105,000 to establish multi-level HIV prevention/education intervention; the Milwaukee Indian Health Board, $129,000 to conduct HIV/AIDS prevention assessment; the Family Health Projects Inc. of New York City, $104,000 to launch prevention programs targeted at homosexual and bisexual Asians and Pacific Islanders. Northern Virginia received $59,152 to conduct needs assessment of prevention education; the Plainfield, N.J., Division of Health received $56,152 to coordinate prevention programs for women at risk of HIV; the Wake County, N.C., Department of Health was granted $101,998 to conduct community assessment of HIV and STD prevention; the San Bernadino County, Calif., Department of Health received $100,000 to establish a community outreach program; the Puerto Rico Community Network For Clinical Research on AIDS was provided with $102,657, to incorporate new prevention services into existing strategies using street outreach activities and risk reduction workshops; and Lucas County, Ohio, District Board of Health was given $121,356, to conduct a needs assessment on prevention services that target specific populations. Dapsone-Pyrimethamine Compared With Aerosolized Pentamidine as Primary Prophylaxis Against Pneumocystis Carinii Pneumonia and Toxoplasmosis in HIV Infection * New England Journal of Medicine (05/27/93) Vol. 328, No. 21, P. 1514 Girard, Pierre-Marie et al. Aerosolized pentamidine and dapsone-pyrimethamine were found to be equally effective in preventing first episodes of Pneumocystis carinii pneumonia (PCP) in HIV-positive patients, but dapsone-pyrimethamine was not as well tolerated as aerosolized pentamidine when used to treat toxoplasmosis, write Pierre-Marie Girard et al. of the Institut National de la Sante et de la Recherche Medicale in Paris, France. The researchers conducted a randomized trial that compared two prophylactic regimens: dapsone (50 mg per day) plus pyrimethamine (50 mg per week), and aerosolized pentamidine (300 mg per month). The patients had symptomatic HIV infection, no history of PCP or symptomatic toxoplasmosis, and CD4 counts below 200 per cubic millimeter. In an intention-to-treat analysis, after a median follow-up of 539 days, PCP developed in 10 patients in each group, whereas toxoplasmosis developed in 32 of 176 patients in the pentamidine group and 19 of 173 patients in the dapsone- pyrimethamine group. Those assigned to pentamidine had a risk of PCP that was similar to the risk in those assigned to dapsone-pyrimethamine. Among the 262 patients with serologic evidence of past exposure to Toxoplasma gonii, the relative risk of symptomatic toxoplasmosis was 2.37 times higher in those assigned to pentamidine. More patients had to be taken off of dapsone-pyrimethamine than pentamidine because of the toxicity. Global Emergency * Mclean's (Canada) (05/24/93) Vol. 106, No. 21, P. 52 Chisholm, Patricia The number of tuberculosis cases is increasing worldwide, mostly in Third World nations. Between one-third and one-half of the global population has tubercle bacillus, the bacteria responsible for TB. World Health Organization officials have issued a worldwide emergency and reported that 30 million people will die from TB in the next decade unless the malady comes under control. Although Canadians have not seen a major increase in TB cases, officials are concerned that a trend of annual declines in the number of reported cases has abated. Health officials gauge the number of Canadians infected with HIV to be 35,000, who has a dramatically higher risk of contracting TB because of its members' depressed immune systems. Treatment for TB usually requires more than one drug over at least six months. Individuals with TB can spread the disease to other people by coughing or sneezing. Nearly 50 percent of new cases remain in areas of the world where the disease runs rampant, including Asia, Africa, Central America, and South America. Canada has strengthened its refugee laws to prevent immigrant children from infecting Canadian schoolchildren. Natives, who make up 20 percent of new TB cases in Canada, have a greater risk than the general population. June 2, 1993 IBF to Consider Testing for HIV * Washington Post (06/02/93), P. C2 An executive committee of the International Boxing Federation (IBF) yesterday made a unanimous recommendation to the federation that any fighter seeking an IBF title should have to prove in some way that he is not infected with HIV. The committee voted, 11-0, in Albuquerque, N.M., to present to the convention of the IBF and its parent body, the United States Boxing Association, a measure that will require promoters to ensure that all those seeking championships are HIV-negative before the fight is sanctioned. The entire body will be presented with the motion today. Robert W. Lee, president of the IBF, said, "I expect it will pass." The recommendation comes after Ruben Palacio of Colombia was stripped of his title last month as the World Boxing Organization featherweight champion because he tested HIV-positive in a prefight physical. Fla. Drug Firm Testing Anti-AIDS Product * Journal of Commerce (06/02/93), P. 7A A pilot laboratory has been built by a renowned Florida medical firm in order to produce clinical trial quantities of HIVIG, a blood product designed to block the transmission of HIV from infected mothers to their unborn infants. North American Biologicals Inc. (NABI) has also submitted an application for a special permit from the Food and Drug Administration for its Coconut Grove facility to become a collection site for the processing of HIV-infected plasma. David Gury, NABI's chairman and chief executive, said preliminary data suggest that HIVIG might be effective in preventing the spread of HIV from mother to baby. NABI, which is one of the world's largest independent providers of human blood plasma, acquired the rights and assets related to HIVIG from Abbott Laboratories last year. What's News: The AIDS Epidemic ... * Wall Street Journal (06/02/93), P. A1 The AIDS epidemic will continue to devastate the world for at least one or two more generations, even if researchers discover a successful vaccine in the next few years, said the chairman of the international AIDS conference scheduled to begin Monday in Berlin, Germany. Karl-Otto Habermehl, who heads a virology institute, said that the epidemic has not yet peaked in its severity. AIDS Enters Second Decade Amid Debate on Progress Toward Cure * Reuters (06/01/93) Johnson, Cynthia (London) The AIDS epidemic, now in its second decade, is still surrounded by controversy regarding its prevention and cure. Worldwide attention will again concentrate on the prospects for fighting AIDS next week at the ninth international conference on AIDS in Berlin. Although AIDS activists criticize today's AIDS research, many scientists say the progress of research is unprecedented, especially considering the complexity of HIV and its mutability. Since HIV was first discovered, its genes have been documented and two variants, HIV-1 and HIV-2, have been found. The World Health Organization and the Centers for Disease Control found no evidence of a third AIDS-like virus after reports of cases of severe immune system depression in the absence of either variant of HIV. A recent survey by the Pharmaceutical Manufacturers' Association (PMA) found that 17 drugs had been approved in the United States to treat AIDS and AIDS-related conditions at the end of last year. Combination drug therapy is generally accepted to be the most effective treatment for HIV-positive patients because the virus quickly builds up drug resistance. The drugs used in combination therapy will most likely include the nucleoside analogs AZT, DDC, and DDI. Other antivirals being tested include tat inhibitors and protease inhibitors. About 15 vaccines are currently in clinical trials. Dr. Joep Lange, head of clinical research at WHO's Global Program on AIDS, said that the most promising vaccine in animal trials uses a live, genetically- modified virus. Health Professionals Announces Appointment of Director of Research as HIV Standards of Care Editor * Business Wire (05/28/93) (Fort Lauderdale, FL) Health Professionals Inc. (HPI) on Friday named Dr. William M. Reiter, HPI's CEO and the Director of Research for its Center for Special Immunology Inc. subsidiary, as Editor-in-Chief of a new annual "Standards of Care for HIV Disease" publication to be issued by the Physicians Association for AIDS Care (PAAC). In 1987, PAAC was established as a nonprofit association of physicians and healthcare professionals intended to provide medical education and influence public policy concerning AIDS. PAAC has about 800 members in the United States who have cared for more than 100,000 people with HIV infection or AIDS. "As a greater number of physicians are beginning to care for people with HIV disease, it is critical that AIDS specialists share their expertise with their colleagues. A peer-reviewed series of treatment algorithms could have a significant impact on extending the lives of hundreds of thousands of people with HIV and AIDS," said Gordon Nary, executive director of PAAC. Dr. Reiter said, "The first publication will be released after including new clinical information to be presented next month at the IXth International Conference on AIDS." HPI, through its principal subsidiary Center for Special Immunology Inc., runs a national network of facilities that incorporate primary care and clinical research in immunologic disorders--mainly for patients with HIV infection and AIDS. Condom Use in Nation's Capital Surveyed * United Press International (05/27/93) (Atlanta, GA) Among Washington, D.C., residents surveyed, more than half reported always using a condom during sexual activity, according to a report by the Centers for Disease Control. However, these findings suggest that about 40 percent are still not consistently protecting themselves and others from the spread of sexually transmitted diseases such as HIV infection. The CDC's report said 59 percent of people in the nation's capital between the ages of 18 and 45 who said they had sex with more than one partner in the past year reported always using a condom. But about 40 percent of sexually active people in the District were having unprotected sex with multiple partners. The study also found that 70 percent of men with more than one sex partner reported always using condoms. The research was conducted by the District of Columbia Commission of Public Health and was based on information from random telephone calls involving 578 respondents. Between 1980 and 1990, the rate of AIDS cases in Washington, D.C., was 2,713 cases per 100,000 persons--about eight times that of the surrounding metropolitan area, where the prevalence of the disease was 340 cases per 100,000 individuals. AIDS Activists Heckle Clinton Over Haitians * Reuters (05/28/93) (Philadelphia, PA) AIDS activists disrupted President Clinton's speech at Philadelphia's City Hall last week by chastising his policy regarding the HIV-positive Haitians detained at the U.S. Naval Base in Guantanamo Bay, Cuba. The protesters unfurled a large banner with the message, "Abolish AIDS concentration camps," and began chanting "H-I-V is not a crime. Free the Haitians." Clinton told the crowd that had gathered to hear his speech, "My budget did more to fight AIDS than any in history and we're having to put up with this." As the activists continued to frustrate the president, he told the crowd, "I'll make you a deal--I'll ignore them if you will." The crowd expressed its agreement, and Clinton gave the rest of his speech, interrupted only a few times protesters. Proposal for AIDS Memorial Dropped * St. Louis Post-Dispatch (05/28/93), P. 3A Yearwood, Lori Teresa A proposed memorial to people who have died of AIDS was rejected by St. Louis, Mo., city park officials as being inappropriate and too costly to maintain. Gary Bess, acting director of the city parks department, said, "If we can create some positive public space for the public to enjoy, that's what we like to encourage. But we don't want a memorial to the dead." Consequently, Howard Meyer is taking his idea to establish an AIDS memorial somewhere else. Meyer said of the city's decision, "I think it's one of the grandest scales of homophobia I've ever seen in my life--just plain bigotry." Meyer had proposed to renovate the Vandeventer Gateway in Forest Park with inlaid eight-inch slabs of granite with the names and ages of St. Louisians who died of AIDS. Activists said that the memorial, intended to be a place of contemplation, would be the first of its kind in the United States. Meyer had hoped to generate the needed money through his nonprofit group, St. Louis AIDS Memorial Inc., and a federal grant. City park officials initially thought the memorial would consist of a small plaque and discreet landscaping, but when they saw Meyer's actual design--which was 240 feet wide--they objected. Although officials claim that the proposed grass hills and flower beds at the memorial would be too difficult to care for, the architect of the memorial said it would not take more than a lawn mower to maintain. Meyer said he will continue to fight the city and if he doesn't succeed there, he will purchase land for the memorial. The Dual Epidemics of Tuberculosis and AIDS: Ethical and Policy Issues in Screening and Treatment * American Journal of Public Health (05/93) Vol. 83, No. 5, P. 649 Bayer, Ronald et al. Because of the epidemiology of the tuberculosis epidemic, its relationship to HIV infection, and the fact that it is the most socially marginalized individuals who are affected by TB and HIV, there is a danger that the demands by the public for increased health protection will foster a climate in which the rights of infected individuals may be ignored, write Ronald Bayer et al. of Columbia University. The authors write that mandatory HIV testing is not essential to effective TB control, and that although individuals infected with HIV are at increased risk for developing TB, exclusionary employment practices are not justified. Because neglecting to complete the regimen of anti-TB treatment increases the potential for the development of drug resistance, it is imperative to require all those who start treatment to finish it completely. In order to safeguard against the development of drug resistance, special attention must be given to the needs of the homeless, drug users, and those with psychiatric disorders. Moreover, all TB patients should start their post-hospital care under direct supervision. Those patients who fail to complete treatment should be subject to confinement after a hearing with full due process protection. Factors Affecting Gay and Bisexual Men's Decisions and Intentions to Seek HIV Testing * American Journal of Public Health (05/93) Vol. 83, No. 5, P. 701 Myers, Ted Improving access to HIV testing by removing some of the current psychological and physical barriers will enhance its medical and public health significance, write Ted Myers et al. of the University of Toronto in Ontario. In the spring of 1990, 1,295 men completed an anonymous questionnaire in gay-identified bars and bathhouses in Toronto. About 53 percent of the respondents had been tested for HIV infection, of whom 26 were found to be HIV-positive. Metropolitan residence was most strongly associated with previous test seeking. This could be due to the heightened awareness of the risk of HIV infection and the extensive HIV/AIDS education that has taken place in urban areas. In addition, residents of metropolitan areas have access to an established and supportive gay community along with relatively greater anonymity than residents of more rural areas. The study also found that older men and bisexual men were more resistant to being tested for HIV. The smaller proportions of older and bisexual men seeking testing may reflect the lower prevalence of high-risk behavior among these groups. The finding may also be related to sexual identity and openness. Furthermore, the study found that previous test experience was strongly associated with intention to be tested. Reasons for not being tested included: desire for anonymity, self-perceived health, and no benefit and denial. Bisexuals and men who did not engage in anal sex were more likely to express a desire for anonymity. June 3, 1993 Youth AIDS Prevention Efforts Faulted * Washington Post (06/03/93), P. A5 The National Commission on AIDS yesterday suggested in a report that the lack of an aggressive federal AIDS policy has left young people confused and vulnerable to the disease. The commission's report also urged that condoms be provided in schools, but that abstinence be stressed as the most effective means to avoid contracting HIV infection. "Years of disagreement at the highest levels of the federal government over the proper messages to give young people have helped to create and perpetuate a national atmosphere of confusion and controversy," said the report. The commission advised that a "vigorous and unequivocal leadership" in a broad new educational effort is needed to teach America's youth about the risks of HIV infection and how to prevent its transmission. The commission released a second report yesterday that urged private businesses, as well as the government, to devise AIDS education programs and workplace policies for HIV-positive employees. "At too many work sites, managers and employees are in states of denial, complacency or ignorance--all of which can have adverse consequences for individuals and organizations," the report said. The National Commission on AIDS is currently in the last stages of preparing a final report to the president scheduled to be released at the end of the month. Although Presidents Ronald Reagan and George Bush opposed the distribution of condoms, President Clinton's position on the issue is still unknown. Related Stories: Los Angeles Times--Washington Edition (06/03) P. A5; Philadelphia Inquirer (06/03) P. A2; Baltimore Sun (06/03) P. 13A. AIDS Virus Isolations in U.S., France Traced to Same Patient * Philadelphia Inquirer (06/03/93), P. A2 The original samples of HIV that were isolated by researchers in France and other researchers in the United States in the early 1980s appear to have come from the same patient, according to a study published in today's issue of the journal Nature. The study said that the virus from the patient apparently tainted a laboratory culture used in the United States to isolate HIV. Earlier work demonstrated that the patient's virus also contaminated French laboratory cultures from which the French isolate was taken. The French and American labs shared material from their cultures, unknowingly allowing contamination in both labs. The study's conclusion reaffirms what researchers had said about the striking similarity between the strain of HIV isolated by the U.S. National Cancer Institute and the Pasteur Institute in Paris. Thomas White and colleagues at Roche Molecular Systems Inc., who conducted the study, examined the genetic material from HIV samples. They concluded that the pool of HIV from which the cancer institute isolated its virus was contaminated between October 1983 and early 1984. The tainted virus was initially recovered from a patient identified as LAI. Schools Give Condoms to 1,600 in First Year * Washington Post (06/03/93), P. D.C. 1 Harris, Hamil R. In the first year of Washington, D.C.'s condom distribution program in schools, nearly 1,600 students, or 9 percent of students in targeted schools, have requested condoms at least once, while hundreds of others have returned more than once. D.C. Public Health Commissioner Mohammad Akhter said, "This is the most successful school health program in the country, and the proof is in the data." He said that while a cause-and- effect correlation would be hard to prove, preliminary data suggest 300 fewer teenage pregnancies this school year and a 30 percent decrease in sexually transmitted diseases among teenagers. Overall, 20,000 condoms have been provided for students since October. Health officials say requests for condoms, which were offered in all of the high schools and four of the city's 25 junior highs, far surpassed expectations as the school year progressed. Twice as many condoms were given to young men than young women, and the average age of recipients was 16, said health officials. Before students are allowed to receive condoms they must attend two assemblies on health issues, including a discussion of AIDS. They also must attend a private counseling session with a school nurse. The condom distribution program was started this year in order to slow the spread of AIDS. Recent studies show that HIV is spreading faster in Washington than in any other major U.S. city. Research has also indicated that one in every 45 District teenagers may be HIV-positive. State Increases Funding to Phila. AIDS Hospice * Philadelphia Inquirer (06/03/93), P. B2 Pennsylvania Gov. Robert Casey's administration yesterday revealed plans to allot $615,000 in funds this year for Betak, the Philadelphia hospice and nursing care facility for AIDS patients. The amount announced yesterday is a $200,000 increase from the $415,000 contract for 1993-1994 that the state approved in April. The Rev. L. Tiemeyer, president of Lutheran Home at Germantown, Betak's parent company, had said in April that an additional $250,000 would be necessary in order for the facility to stay open past June 1. State officials said in their announcement that the Betak facility might receive as much as $359,000 more for expenses during the last fiscal year. The additional funds would not come from the state, but from other revenue sources involving medical assistance reimbursements that were available to Betak but that the facility has not yet claimed. Miss America Censored in Fla. Over AIDS Views * Baltimore Sun (06/03/93), P. 13A Miss America Leanza Cornett, who enjoys educating people about AIDS, has been asked not to mention the disease when talking with elementary school students in Florida. Some school officials demanded that she not use the word "condom" when talking to students, while others advised that she not mention AIDS at all. "When the notice said I couldn't talk about AIDS or sex, I was floored," said Cornett. She was told not to mention the disease when visiting three elementary schools Tuesday in Bradford County, Fla. "I can adhere to any school board's needs. But I will not be an accomplice to the spread of this disease," she told a Rotary-Kiwanis meeting after her school visits. She added, "People are dying from this disease. I feel guilty that I didn't speak about it. I don't want to lay blame, but the school board should feel guilty." She went to the schools to present awards for Chevrolet's "Driving for Education" program, and gave 10-minute motivational speeches to the students. Jo Ann Rowe, the Bradford County school superintendent, said Wednesday that school officials must inform parents in advance if an outside speaker is going to discuss sexual issues such as AIDS. The disease is addressed in the fifth grade and in sex education in the sixth grade, according to the school district's curriculum. Cornett indicated that this is not the first time she has been told not to discuss AIDS. AIDS Conferences Have Outlived Usefulness, Journal Says * Reuters (06/02/93) They should be replaced by more effective means of communication, according to an editorial in the British journal Nature. The editorial on next week's ninth international conference on AIDS in Berlin said, "For those who wish to catch public attention, say for an untested candidate vaccine, the announcement of research collaboration or the denunciation of the 'AIDS hypothesis,' Berlin will be a splendid venue." It added, "None of this implies that no serious science will be done but merely that ... AIDS conferences have outlived their usefulness and should be stopped." The editorial said that these annual conferences began at a time when it appeared there might be rapid progress toward treatment and a cure for AIDS. It was only natural that the research community would report back at regular intervals on its findings. "The implied promise has already been broken. The biomedical research community cannot in logic be blamed that the AIDS virus has turned out to be a more obdurate agent than originally expected, but it is blamed," the editorial said. With no cure in sight, the public- -as opposed to professional--interest has changed its focus from biomedical affairs to the alteration of human behavior as a means of preventing HIV, the journal said. "Does one have to travel to Berlin to hear that?" the editorial asked. Health Professionals to Present Research at Berlin AIDS Conference * Business Wire (06/02/93) (Fort Lauderdale, FL) Health Professionals Inc. (HPI) has announced that its principal subsidiary, Center for Special Immunology Inc. (CSI), will be presenting two research reports at the Ninth International AIDS Conference in Berlin next week. CSI's Immune Reconstitution Treatment program will present its first findings in a paper entitled Treatment of Late-Stage AIDS Patients with Combined Monthly Anti-HIV Hyperimmunoglobulin and Haplotype-Matched Peripheral Blood Lymphocytes. The study was intended to directly boost immune system function in patients with progressive HIV infection and late-stage immune system depletion. The second study, Cytotoxic CD8 Lymphocyte Response to HIV-1 Infection Correlated with Longitudinal Analysis of CD4 Lymphocyte Percentage, provides insight into how advanced laboratory testing can be used to estimate response to treatment over time. Dr. William M. Reiter, Director of Research for CSI and Chairman and CEO of HPI, said, "These two CSI papers have been accepted for oral platform presentation, the highest level of presentation at the International AIDS Conference." Pregnancy and Contraception Use Among Urban Rwandan Women After HIV Testing and Counseling * American Journal of Public Health (05/93) Vol. 83, No. 5, P. 705 Allen, Susan et al. Additional research is needed to define the cultural, psychological, and practical obstacles to effective, long-term contraception among HIV-positive women, write Susan Allen et al. of the University of California--San Francisco. For two years, the researchers followed a sample of 1,458 childbearing urban Rwandan women aged 18-35 years who were tested for HIV. Upon enrollment, 17 percent of the 998 HIV-negative women and 11 percent of the 460 HIV-positive women were pregnant, and 17 percent and 23 percent, respectively, were using hormonal contraceptives. One year later, half of the HIV-infected and one third of the HIV-negative hormonal-contraceptive users had discontinued use. The two-year incidence of pregnancy was 43 percent in HIV-positive women and 58 percent in HIV-negative women. HIV-positive women with fewer than four children were more likely to become pregnant than those with four or more children; this correlation persisted in multivariate analyses but was not noted among HIV-negative women. At the conclusion of the study, more than 40 percent of contraceptive non-users said that they would use hormonal contraceptives if they was provided at the study clinic, but 40 percent of the HIV- infected women wanted more children. Community programs are needed to increase resources and options for HIV-infected women and their children, and to allow HIV-positive women to be valued and supported even if they have relatively few children, the researchers conclude. Bar Codes Track HIV Infected Needles * IDSystems (05/93), P. 27 Navas, Deborah The clean-needle exchange program in New Haven, Conn., has successfully thwarted the spread of HIV among IV-drug users by using an advanced system of tracking the needles and infection rates. The AIDS intervention program conducted by Yale University and New Haven's health department has used the bar- code-based syringe tracking and testing (STT) system for about three years, and the resulting data strongly indicate that needle exchange significantly slows the rate of infection without encouraging new drug use. Edward H. Kaplan, a professor at both the Yale School of Management and the Yale School of Medicine, helped develop the STT system. It is based on coded syringes, which makes it possible to obtain accurate, quick, and modest estimates of needle return rates, circulation time, and changes in the rate of infection among needles distributed by the program. New Haven health workers distribute clean needles with six-digit sequentially numbered labels identifying them. They frequently travel in a van to the inner city where drug use is prevalent. The clients enter the van and identify themselves by code names to ensure anonymity. The drug users put their old syringes in a labeled needle caddy, and in exchange they receive kits that include bleach, water, clean needles, and condoms. The coded needles link a number of variables with the individual returned needle. This information is subsequently entered into a computer on location. The returned needles are later scanned with Datalogic DL 60 CCD scanners, samples are tested for HIV, and the results are added to the tracking database. This data made it possible to ascertain reliable statistics and timely information on the program's effectiveness. AIDS: The Silent Treatment * Health (05/93-06/93), P. 16 Doctors do not educate their patients enough about AIDS, according to a study by researchers from the University of California. The researchers questioned 1,312 people if, during medical checkups in the past five years, a physician had discussed AIDS or asked them about high risk sexual behavior. Those who said no accounted for 80 percent. When AIDS was addressed, doctors initiated the conversation only 21 percent of the time. According to psychologist Barbara Gerbert, one of the authors of the report, doctors assume that patients who believe they are at risk for HIV infection will ask the questions. However, the survey found that less than a quarter of people in high risk groups had brought up the issue. "Doctors must think patients wear signs saying, 'I'm the one to talk to about AIDS,'" says Gerbert. June 4, 1993 Around the Region: Teacher Charged in Sex Abuse Tests Negative for AIDS * Washington Post (06/04/93), P. D5 The former Anne Arundel County, Md., high school teacher who has admitted to having sex with seven students has tested negative for HIV, according to his attorneys. The lawyers also said that he may plead insanity when his case goes to trial. Ronald W. Price. who was arrested on April 8 and charged with three counts of child sexual abuse, has suggested that he is innocent because his actions were a result of a mental illness. Price recently indicated that he may have been exposed to HIV but was found to be HIV-negative after an Anne Arundel County Circuit Court judge had allowed him to leave his home to get tested. Stepping Ahead of AIDS Walk * Boston Globe (06/03/93), P. 23 Artis, Joanne Ball The 8th annual From All Walks of Life--AIDS Pledge Walk in Boston will be held Sunday. Vance Deare, an AIDS outreach worker, has been urging the minorities he works with to participate in the AIDS fundraiser for the past three months. Deare, who is also a minority, said it has been a difficult challenge working with this population. "The minority community is in a real state of denial about the disease. They believe that if we don't deal with it, it will go away. But for a host of reasons, we are more affected by it," he said. Massachusetts AIDS statistics released last week showed that the trend of the epidemic is affecting even greater numbers of minorities and women. The escalating number of cases makes Deare's mission all the more important. Deare expects this year's AIDS walk to have the highest representation of minorities ever, as a result of his efforts. About 35,000 people were involved in the walk last year, which raised $2.95 million for 35 AIDS organizations and agencies in eastern Massachusetts. Bradley Seeman, walk manager at the Boston-based AIDS Action Committee, said, "What makes the walk so powerful is that tens of thousands of people will be walking, asking for donations from hundreds of thousands of other people. It really makes it an enormous grass-roots effort." Detained Teenagers Walk for AIDS Research Inside Detention Center * Boston Globe (06/03/93), P. 29 Hart, Jordana About a dozen teenagers at a Massachusetts detention center, who the state will not allow to participate in the annual 10- kilometer AIDS Pledge Walk in Boston this Sunday, raised money on their own on Wednesday by circling their fenced yard 52.5 times. Janet Martin, director of the Boston Secure Treatment Center, a program at Roslindale detention center, said yesterday's incident was the second such 10-kilometer "yard" walk for youths held at the detention facility. After employees at the detention center last year decided to participate in the walk, some of the youths also expressed interest in the event, but they were not allowed to participate because they were incarcerated, said Martin. She added that the boys "raised more than $1,000 last year." "We have two boys here who have lost both parents to AIDS. Others know people who have AIDS or who have died of AIDS," said Martin. Department of Youth Services spokeswoman Christy George said the teenagers' walk, which was voluntary, started at 10 a.m. and continued until noon, then resumed at 1:15 p.m. and ended at 3:30 p.m. The treatment program at the center offers a course in sex education, which includes information on AIDS and HIV. George said, "We consider these kids at risk for AIDS, not because of intravenous drug use, but because of sex and not using condoms." Medizone's Blood Decontamination Technology Proven Successful in Canadian Monkey Trial * Business Wire (06/02/93 (New York, NY) Medizone International Inc. on Wednesday disclosed that it had successfully completed the first two phases of a Canadian research study that has shown preliminary scientific evidence supporting the use of the company's proprietary blood decontamination technology in monkeys. "To date, the research program has successfully demonstrated that monkeys receiving blood fractionated plasma purposely infected with a highly virulent strain of Simian Immunodeficiency Virus [monkey equivalent to HIV], but treated with Medizone's process, did not demonstrate any signs of infection over the course of the study [35 days]. However, all animals receiving similarly infected products without the benefit of intervention of Medizone's decontamination technology died within 12-14 days," said Dr. Joseph S. Latino. In addition, he said, "These preliminary research results indicate the capability of Medizone's patented scientific and technological process to inactivate blood and blood products of certain viral contaminants, including the AIDS virus." Those who conducted the research included scientists from the Canadian Red Cross, Canadian Departments of Defense and Agriculture, Cornell University Veterinarian Medical College, and Medizone Canada Ltd., concluded Latino. Irish Government Approves Condom Vending Machines * United Press International (06/03/93) (Dublin, Ireland) The Irish government on Thursday voted in favor of lifting the ban on the sale of condoms through vending machines. The move is considered a milestone in the liberalization of the country's rigid laws on moral issues. Despite strong opposition from the Catholic church, the government also eliminated the ban on the sale of condoms to people under 17 years of age. The new laws call for condom vending machines--previously illegal in Ireland--to be installed anywhere except for schools, and the advertising ban on condoms is expected to be lifted. Ireland's health minister, Brendan Howlin, commended the government's effort as a landmark in the fight against AIDS. However, the Irish Catholic church argued that lifting the ban would result in a moral decline in Ireland. Spokesman of the Irish Catholic Bishop's Conference, Bishop Joseph Duffy, said, "Laws which provide for the widespread availability of condoms can give the appearance of society's approval for an abuse of God's gift of sexuality." The new condom sales policies bring an end to 25 years of campaigning to bring Ireland's strict anti-contraceptive laws up to the pace of most Western countries. French Catholic Archbishop Backs Condom Use * Reuters (06/03/93) (Toulouse, France) A French Roman Catholic archbishop revealed Thursday his support for condom use, which challenges the teachings of Pope John Paul II. Andre Collini, archbishop of Toulouse in southwestern France, said the church should rethink its doctrine on forbidding condom use because the devices are the best known method for preventing the spread of HIV infection. "If one cannot change one's sexual habits, then one does not have the right not to use a condom because that would mean becoming an agent of death, and the [fifth] commandment says thou shalt not kill," said Collini. Even though Collini's views are backed by many liberal-minded Catholics, it was highly unusual for someone of his rank to contradict the tenets of church doctrine. The pope emphasizes that abstinence is the only way to prevent contracting HIV. But his position on AIDS has angered many liberals who accuse the pope of irresponsibility. ImmuCell Announces Continued Clinical Program to Develop Treatment for Diarrheal Infections in AIDS and Other Patients * Business Wire (06/02/93 (Portland, ME) ImmuCell Corp. on Wednesday announced the continuation of the Phase I/II human clinical trials for CryptoGAM, an orally administered polyclonal antibody product for the treatment of cryptosporidiosis in AIDS patients and others with weakened immune systems. The trials are being conducted by Univax Biologics Inc. of Rockville, Md., the licensee of the marketing rights to CryptoGAM. Univax has completed a Phase I/II trial involving 40 AIDS patients with chronic cryptosporidiosis. About 10 percent to 15 percent of all AIDS patients in the United States experience cryptosporidium infection, which often leads to death. Cryptosporidium parasites attack the small intestine and cause extreme and often debilitating diarrhea. There is no effective treatment currently available for the condition. The antibodies used in CryptoGAM are grown in cows immunized with a vaccine developed by ImmuCell. Univax President and CEO Thomas P. Stagnaro said in a quarterly letter to Univax shareholders on June 2, "Our first controlled study under a Univax IND (Investigational New Drug Application) accomplished its goal of demonstrating safety and showing activity. A truly effective product for this indication would not only reduce parasite counts but also reduce diarrheal volume. In our study, the parasite level was reduced; however, diarrhea volume remained unacceptably high in some patients." Univax expects to continue enrolling patients to analyze higher doses and possible alternative delivery modes of CryptoGAM. More Guantanamo Haitians Released * United Press International (06/01/93) (Miami, FL) An additional 11 HIV-positive Haitian refugees held at the U.S. Navy base at Guantanamo Bay, Cuba, were admitted into the United States last weekend. The 11 refugees was flown to the United States during the weekend and paroled into the community for humanitarian reasons, said Duke Austin, a spokesman for the Immigration and Naturalization Service. "These all had minor children," said Austin. One family of six was brought to New York City and the other family of five will reside in Homestead, Fla. Meanwhile, 160 Haitian refugees remain at the naval base. Austin said, "We're looking at all of them individually. We have some pending requests for paroles. Their medical conditions are still being monitored." Approximately 50 HIV-positive Haitian refugees were allowed to enter the United States last month under a judge's order that the government provide sufficient medical care for those with full-blown AIDS. U.S. District Judge Sterling Johnson in New York, who made the ruling, is still reviewing a lawsuit regarding the fate of the other refugees. Life Insurers Plan AIDS Tests * Nikkei Weekly (Japan) (05/24/93) Vol. 31, No. 1570, P. 19 As an increasing number AIDS cases begin to appear in Japan, the life insurance industry there plans to require HIV tests of applicants before issuing policies. Japanese insurance industry officials said the issue at hand is how to safeguard the privacy of test results--not the validity of rejecting applicants. Insurance companies already conduct physical examinations, and deny coverage to people with terminal cancer or other severe conditions. However, the physical currently does not include an HIV test, and insurers pay benefits in AIDS-related deaths. The industry is concerned that without a means to screen applicants for HIV, payments will escalate, thereby reducing profits. "If the number of AIDS victims continues to increase, we would be forced to boost premiums, burdening all those wanting life insurance," one senior executive in the insurance industry said. The Life Insurance Association of Japan has formed a committee to examine the details of requiring an HIV test. The committee could issue a plan as early as this fiscal year after it consults with health-care professionals and examines the U.S. situation. Some in the industry predict that it will take considerably longer to implement an HIV testing requirement. Court Order on Infected Inmates * American Medical News (05/24/93) Vol. 36, No. 20, P. 2 A federal judge has ordered that California prison officials place HIV-positive inmates in food-service jobs at the Vacaville medical prison. According to U.S. District Judge Lawrence Karlton, the state's ban on HIV-infected inmates in food jobs is illegal under the Americans with Disabilities Act because the institution receives federal money. He ruled that food-service assignments be given to HIV-positive inmates who are in the first six months of infection. NOTE: Compilation by Michael Tidmus : AIDSwire. All rights reserved. Permission is granted to republish on electronic media for which no fee is charged, provided the complete text of this notice is attached to any republished portion or portions. * From the AIDS Daily Summary. The Centers for Disease Control and Prevention (CDC) National AIDS Clearinghouse has made this information available as a public service only. Providing this information does not constitute endorsement by the CDC, the CDC Clearinghouse, or any other organization. Reproduction of this text is encouraged; however, copies may not be sold. Copyright 1992, Information, Inc., Bethesda, MD. -----===[[[ A I D S w i r e D I G E S T 05.31.93 ]]]===------ .