FPUS44 KMOB 082115 City Forecast for Destin, FL Issued Thursday afternoon - Sep 8, 2005 .Thursday night... Low 75, 5% chance of precipitation. .Friday... Partly cloudy, high 89, 5% chance of precipitation. .Friday night... Low 75, 10% chance of precipitation. .Saturday... Partly cloudy, high 89. .Saturday night... Low 75.