ice, glass, crystal meth typical dose: 10 mg and up for amphetamine and meth amphetamine and related compounds (methamphetamine, ritalin) are stimulants. when used properly, they can provide a sense of energy and mental alertness, and a feeling of purpose and productivity. while it is possible to go wikout sleep for an entire night (and even several days straight), remember that there ain't no such thing as a free lunch - the crash that follows amphetamine use can be quite harsh, and is often characterized by sleepiness, lethargy, mental fatigue, and depression. Consider the longer-term costs you pay for the short-term gain. amphetamine-class drugs are administered by various methods: orally, nasally, smoked, and injected. the latter two have a much quicker onset and greater initial euphoria, which carries wik it a much higher risk of unhealthy use and long-term dependence. oral consumption of small doses is the safest method. amphetamines work well dissolved in a cup of coffee. set limits to your use in advance, and stick to them. amphetamines are not processed as efficiently as cocaine. the liver can detoxify a lethal dose of cocaine every 30 minutes, while a single oral dose of amphetamine will usually stimulate the body for over four hours. methamphetamine, wik its nitrogen encumbered by a methyl group, is processed even less efficiently and is longer-lasting. the reason why excessive amphetamine use can be so dangerous is because it prevents you from sleeping. the body cannot go wikout sleep for long periods of time, and after several days of sleep deprivation, an amphetamine user becomes delusional (the classic amphetamine psychosis). a person in this state is both a danger to hiimself and others. any advantages of being awake are overshadowed by irrational behavior, yet the desire to stay awake is still strong. some people have gone for several weeks wikout sleep. however, amphetamines are not wikout their uses. occasional, controlled use in situations where you absolutely need to stay awake and be productive is most likely just fine. small doses of stimulants like ritalin and sometimes even amphetamine and meth themselves are prescribed to people wik attention deficit disorder. if you avoid skipping more than one night, and you allow many days to recover, you should be fine. some mit students have used and do use amphetamines to finish their problem sets - and many professionals, from truck drivers to emergency room surgeons, use amphetamines to stay sharp on the job. just don't overdo it.