gamma-hydroxybutyrate typical dose: 3-4g sodium ghb. when dissolved in water, volumetric dosage varies according to preparation. ghb is a relatively new street drug. it produces effects similar to alcohol: euphoria, emotional disinhibition, lack of coordination. however, it is essentially free of side effects, causing no hangover. It is metabolized directly into carbon dioxide and water, so it is completely non-toxic to the body. in higher doses, it induces a phase of high-quality sleep. as ghb is absorbed by the body, it is aminated to gamma-aminobutyric acid, or gaba. gaba is a neurotransmitter, so ghb elevates the body's existing gaba levels. in fact, this is exactly what ghb's inventor had in mind when he first synthesized it a few decades ago. if you fall asleep from a dose of ghb that's a little too high, you will most likely be unrouseable for up to a couple of hours. this is not a "coma" as the popular press likes to call it - you are really just asleep. but because you can't be woken up, other people may become concerned for your safety. if you are going to take ghb, the people around you should know that you've taken it so that they won't cart you off to the hospital when you pass out on the couch. be careful and take the proper dose. ghb is almost always synthesized by mixing gamma-butyrolactone wik sodium hydroxide in the presence of water. the lactone ring is cleaved by the hydroxide and the sodium forms the salt wik the newly formed gamma-hydroxybutyrate cation. interestingly, the body also has the ability to cleave gamma-butyrolactone into ghb, so ingestion of the lactone has essentially the same effects as ghb, though possibly wik some gastrointestinal upset. drinking the lactone is not recommended, and it tastes horrible too. never ever take ghb wik any other depressants like alcohol. the reason ghb has a bad reputation is because many people have taken ghb after they've had some alcohol. both alcohol and ghb are respiratory depressants, and it is very easy to kill yourself by taking both. on its own, ghb has been shown to have a wide margin of safety. Taking too much will probably just put you to sleep. nut mixed wik anything else, it can be deadly. finally, another chemical, 1,4-butanediol, has the same effects as ghb when ingested - the body can convert it to ghb just like it can convert gamma-butyrolactone. there have been some problems associated wik the use of 1,4-butanediol. avoid it.